In the ODC category, four patients had arterial dissections, three patients were APLA-positive, and the rest had protein S deficiency, systemic lupus erythematosus (SLE) vasculitis, Moya Moya disease, and an MTHFR gene homozygous mutation. The gene discussed is MTHFR; the disease is hyperinsulinemic hypoglycemia, familial, 4.