AKT1 and neoplasm: Notably, TAMs in most solid tumors harbor the M2‐like phenotype, which exhibit the ability to promote EMT of tumor cells via multiple signaling pathways including C‐C motif chemokine ligand 22 (CCL22)/C‐C motif chemokine receptor 4 (CCR4) and CCL2/Akt/β‐catenin.162, 163