SLC5A2 and Hyperglycemia: They designed a nondiabetic mouse model (control), a diabetic mouse model without intervention to reduce blood glucose levels (DM-22) and a mouse model of hyperglycemia reversal by sodium-glucose cotransporter 2 inhibitors (SGLT2i, dapagliflozin) (DM-22+SGLT2i) to identify hub genes related to metabolic memory.