ACRV1 and familial pancreatic carcinoma: Biomarker proteins in pancreatic cancer include KRAS (Kirsten Rat Sarcoma Viral Oncogene), MBD3L2 (Methyl-CpG Binding Domain Protein 3 Like 2), DPMI mRNAs (Dolichol phosphate mannose synthase), and ACRV1 (Acrosomal Vesicle Protein 1) [47].