TIGAR and neoplasm: Moreover, increased TIGAR expression was linked with poorer OS in various subgroups, including the T1 subgroup of T stage (HR = 1.83 (1.01–3.34), p = 0.047), stage N subgroup of pathologic stage (HR = 1.77 (1.14–2.76), p = 0.011), Stages I and II of pathologic stage (HR = 1.85 (1.13–3.03, p = 0.014)), G1 and G2 and G3 subgroup of histologic grade (HR = 1.65 (1.15–2.37), p = 0.007), and the R0 subgroup of tumor status (HR = 1.48 (1.02–2.17), p = 0.041) among others (Figure 6b–l).