WWP1, RBM10, ZFY, HIST2H2BF, NRSN2, MARK2, PASK, and RAB5B were relatively highly expressed in the PCa group compared to the prostate hyperplasia group and were statistically significant in terms of difference (P < 0.001)(Supplemental Material 5 and Fig. 4). The gene discussed is NRSN2; the disease is benign prostatic hyperplasia.