It also inhibited the outgrowth of xenografted uveal melanoma cells and patient-derived xenograft (PDX) tumors in NOD-SCID mice and repressed the cancer stem-like cell (CSLC) properties of uveal melanoma through transcriptional inhibition of stemness-related protein Krüppel-like factor 4 (KLF4) [174]. Here, KLF4 is linked to uveal melanoma.