After FDR correction, ABCG5, ABCG8 and APOC3 were found to be signifcantly associated with IPF risk (PFDR < 0.05, Fig. 3), NPC1L1 and PCSK9 had a suggestive effect on IPF risk. The gene discussed is ABCG5; the disease is idiopathic pulmonary fibrosis.