Conversely, the MR analyses did not reveal any causal influence on the risk of IPF from genetic mimicries of HMGCR, LDLR, APOB, LPL, ANGPTL3, CETP, and PPARA inhibitors (all P > 0.05) (Fig. 3. This evidence concerns the gene ANGPTL3 and idiopathic pulmonary fibrosis.