However, in the study by Muller et al., where they measured insulin levels, they found no increased risk of abnormal insulin levels associated with exposure to maternal hypothyroidism in pregnancy (euthyroid [n = 191]: 4.90 μIU/mL, IQR 3.60–6.90, untreated hypothyroid [n = 57]: 4.40 μIU/mL, IQR 3.30–5.7; p = 0.385; Additional file 3) [28]. Here, INS is linked to hypothyroidism.