CNR1 and schizophrenia: We found meta-analytic evidence supporting that CB1R agonists, both natural and synthetic, elicited broad schizophrenia-like behavioural alterations, including impaired working memory [g  = −0.56; (CI: −0.93, −0.18)], novel object recognition [g = −0.66; (CI: −0.97, −0.35)], novel object location recognition [g = −0.70; (CI: −1.07, −0.33]), social novelty preference [g = −0.52; (CI: −0.93, −0.11)], social motivation [g = −0.21; (CI: −0.42, −0.00)], pre-pulse inhibition [g = −0.43; (CI: −0.76, −0.10)], and sucrose preference [g = −0.87; (CI: −1.46, −0.27)].