ERBB2 and neoplasm: Briefly, as a first intention, we used a “candidate strategy” by testing the 45 well-known altered regions/genes (36 amplified genes and 9 deleted genes) described in the eBC tumours from the princeps manuscript of Curtis et al. [19], and as a second intention, we used a “discovery strategy” by screening the entire genome to identify new metastatic-specific CNAs in ER + /HER2− mBCs.