We found that for stromal cells, the predicted dS2 and dS3 specific regulon targets were enriched with preeclampsia downregulated genes, particularly regulon targets predicted for PRDM1 (LOP down p = 1.75 × 10–18, 21-fold) and for FOXP1 (LOP down, p = 3.8 × 10–14, 9.1-fold) (Fig. 6A, Supplementary Table S7). The gene discussed is FOXP1; the disease is preeclampsia.