BCL2L1 and squamous cell carcinoma: This can be observed in the modulation of BCL2 family protein levels by ROS, as heightened pro-apoptotic BAX and BAK1 levels accompanied by a decrease in anti-apoptotic BCL2 and BCL2-like 1 (BCL2L1/BCL-XL) expression are observed in squamous cell carcinoma cells [114].