Genes MIA (Melanoma inhibitory activity) and PLA2G2A (phospholipase A2 group II) show higher specificity as cardiac myxoma markers and certain gene-expressed protein products such as S-100, human calbindin 2, thrombomodulin, basic fibroblast growth factor, fibroblast growth factor receptor 1, transcription factor 9, and transmembrane receptor protein 1 are overexpressed in cardiac myxomas.5 Most of these proteins are associated with tumor proliferation, angiogenesis, and malignant metastasis. Here, PLA2G2A is linked to neoplasm.