The inhibition of miR-374a-5p via exosomes restricts the proliferation, migration, and invasion of HCC cells.34 Additionally, miR-346 has been observed to advance liver cancer proliferation, migration, and invasion through its interaction with FBXL2. 35 There is potential for future HCC research to consider miR-346 as a diagnostic marker and therapeutic target. Here, FBXL2 is linked to hepatocellular carcinoma.