CD8A and ovarian carcinoma: The impaired function of CD8+ T cells contributes to a peritoneal immune imbalance, ultimately facilitating the peritoneal metastasis of epithelial ovarian cancer.196 Yang et al.197 reported that metastasis-associated macrophages (MAMs), which exhibit upregulated CD36 expression, are enriched with lipid droplets due to their enhanced capacity to engulf tumor cell-derived long-chain fatty acids carried by extracellular vesicles.