The pertinence of non-coding RNA in various phases of cancer progression has made it a focal point in contemporary oncological research.31 For instance, 5-methylcytosine, an integral component of the epigenetic regulation network, has been associated with several cellular activities and broader pathologies, including cell migration and cancer metastasis.32 Furthermore, Park et al.33 determined that the lncRNA Neat1 directly interacts to assemble the PGK1/PGAM1/ENO1 complex, subsequently facilitating the glycolysis pathway and promoting tumor metastasis. Here, ENO1 is linked to cancer.