The diagnosis can be obtained according to six clinical criteria, known as the Aicardi criteria.10 One of the cardinal diagnostic criteria of AHC is the remission of hemiplegia and other paroxysmal events, but not seizures, with sleep and their potential recurrence shortly after waking.41 However, in 2012, the molecular abnormality of ATP1A3 was identified as the primary etiology of AHC (Table 2).5,7,23,42,43. The gene discussed is ATP1A3; the disease is alternating hemiplegia of childhood.