HADHA and Barth syndrome: MLCL/CL ratios reported in lymphoblasts from patients with BTHS are 690-fold higher than control levels (44), while in TFP/LCHAD-deficient fibroblasts showing an increase in MLCL/CL ratios, they were 1.4-fold higher than controls in cells from females and 3.8-fold higher than controls in cells from males.