ABCC3 and renal cell carcinoma: On the other hand, inhibition of miRNA-21 in RCC cell lines enhanced chemosensitivity to paclitaxel, 5-fluorouracil, oxaliplatin, and dovitinib by reducing expression of multi-drug resistance genes: ABCC3–6, ABCC2–6, and ABCC3 and ABCC5 [69].