IL2 and early-onset autosomal dominant Alzheimer disease: In the CNS, the expression of IFNα, IL-2, and IL-12 is linked to experimental autoimmune encephalitis (EAE), multiple sclerosis (MS), Alzheimer’s disease (AD), and Parkinson’s disease (PD) (59, 84, 87, 117, 118, 120, –, 122) through amplified Th1 responses (51, 52, 55, 56, 87, 123).