In patients with myocardial infarction, the circulating EOS concentration is elevated for at least 5 days, the plasma ECP concentration peaks on days 2–3 after infarction, and an elevated ECP concentration is positively correlated with the risk of developing IHD; in patients undergoing percutaneous coronary intervention, the plasma ECP concentration is significantly associated with poor prognosis.11, 160. The gene discussed is RNASE3; the disease is myocardial ischemia.