VEGFC and craniosynostosis: Indeed, VEGF-C treatment has been suggested to improve cognition in older mice31, to have synergistic effect with PD-1 treatment to eradicate glioblastoma45, to rescue dLV defects in a craniosynostosis mouse model53, to alleviate effects of CNS viral infection54 or traumatic brain injury-induced gliosis55, as well as to aid the recovery from stroke56 and intracerebral hemorrhage57.