The mechanisms by which Snail exerts its pro-metastatic effects in pancreatic cancer involve suppressing genes crucial for maintaining the epithelial phenotype, such as occludin, E-cadherin, claudin, and cytokeratin-18, while simultaneously promoting the expression of mesenchymal genes like N-cadherin, vimentin, and fibronectin (211). The gene discussed is CDH1; the disease is pancreatic neoplasm.