Four patients operated for GBM IDH wild-type (grade IV) showed EGFR exons 2-7 skipping mRNA with variable levels of the number of fusion reads at 8453, 25600, 31705, and 10214 reads, respectively, to generate EGFR (1)-EGFR (8) RNA transcripts (4/59 gliomas - 6.78%) (Figure 5, Table 5). The gene discussed is IDH1; the disease is central nervous system cancer.