Approximately 40% of people with FTD have a family history (10), and one-third of FTD is inherited by autosomal dominant mutations in three genes: progranulin (GRN), microtubule-associated protein tau (MAPT) and chromosome 9 open reading frame 72 (C9orf72) (11). The gene discussed is GRN; the disease is frontotemporal dementia.