MAPT and frontotemporal dementia: The top 20 keywords included those related to the FTD pathomechanism, such as “Tau,” “Mutations,” “Lobar degeneration,” “Neurodegeneration,” “TDP-43,” “Hexanucleotide repeat,” and “C9orf72.” It has been reported that hyperphosphorylation of MAPT causes FTD (50), presenting tau neurofibrillary inclusion pathology (51).