According to multiple published articles, the components of the m6A writer complex are associated with the promotion of cancer [88-92], however, METTL14, and to some extent ZC3H13, are exceptions that act as tumor suppressors in a variety of cancers [93-96] by stabilizing PTEN mRNA and modulating EGFR/PI3K/AKT signaling pathway. The gene discussed is METTL14; the disease is cancer.