The presence of neurotrophins can help in identifying patients as, at tissue level, the immunostaining for neurotrophins is more intense in GCA versus controls and, particularly, neurotrophin-3 (NT-3) and P75 receptor (P75NTR) are only detected in GCA temporal artery specimens, serving as possible biomarker of disease (Régent et al., 2017). The gene discussed is NGFR; the disease is temporal arteritis.