MANF and focal segmental glomerulosclerosis: Rats with podocyte diseases (experimental membranous nephropathy and FSGS) showed increases in various glomerular ER chaperones and increased urinary non-KDEL chaperones, including ERdj3 (DNAJB11) and mesencephalic astrocyte-derived neurotrophic factor (MANF), coinciding with proteinuria (Tousson-Abouelazm et al., 2020).