These disorders encompass a wide spectrum of neurodevelopmental symptoms, including developmental delay, microcephaly, brain anomalies, intellectual disability, and epilepsy (Gillentine et al., 2021), and have been referred as HNRNP-Related Rare Neurodevelopmental Disorders (HNRNP-RNDDs) by the hnRNP family foundation (see text footnote 1) (Gillentine et al., 2021). Here, HNRNPDL is linked to epilepsy.