The enrichment analysis for these miRNAs yielded 53 significant pathways, some of them associated with cancer and other processes, while many are important in bone development such as the signaling pathways regulating pluripotency of stem cells, the Hippo signaling pathway, the TGF-beta signaling pathway, the PI3K-Akt signaling pathway and the FoxO signaling pathway (52–57). Here, AKT1 is linked to cancer.