The authors further noted that the KA-treated rats that developed epilepsy displayed swifter synaptic glutamate clearance but no changes in GLT-1 or GLAST receptors [Notably, dysregulation associated with both upregulation and downregulation of EAAT1 and EAAT2 has been found in epilepsy (Coulter and Steinhaeuser, 2015; Hubbard et al., 2016)]. The gene discussed is SLC1A3; the disease is epilepsy.