YBX1 and melanoma: According to our proteomic results, in YB-1 expressing melanoma cell line, the highly upregulated proteins were strongly related to ribosomes, mRNA, and spliceosome, which is in agreement with previous studies elucidating the role of cytoplasmic YB-1 as is a part of messenger ribonucleoprotein particles (mRNPs) and a controller of translation and stability of mRNA (Evdokimova et al., 2001; Mordovkina et al., 2020).