CRP and Cryptococcal meningitis: In persons with HIV-associated cryptococcal meningitis, higher baseline serum CRP is associated with increased mortality (adjusted hazard ratio = 1.084 [95% confidence interval (CI), 1.031–1.139], per 10 mg/L increase) [18]; and persons identified as having CRP concentrations in the highest 2 quartiles had approximately 3-fold higher absolute mortality than persons with CRP concentrations in the lowest quartile.