DLK1 and neoplasm: For this reason, Fabian et al. demonstrated a higher effect of combined vaccination against DLK1 and DLK2, with increased antitumor benefits when compared with single-antigen vaccination in both RENCA-bearing mice and B16 melanoma tumor model, leading to vascular normalization and higher recruitment and activation of antigen-specific CD8C TIL (Fabian et al., 2017).