Under inflammatory conditions, such as under LPS, TNFα, or IL-1β stimuli or under tumor microenvironment (TME) influence, pericytes start to release inflammatory cytokines to recruit immune cells (IL-6, IL-8, CXCL1, CXCL2, CXCL3, CX3CL1, CCL5, and CCL2) and upregulate the adhesion molecules ICAM-1 and VCAM-1 (Gaceb et al., 2018). Here, IL6 is linked to neoplasm.