GO enrichment analysis and KEGG pathway enrichment analysis showed that HDW might act on the VEGF signaling pathway and PI3K/AKT/mTOR signaling pathway through synergistic regulation of cell apoptosis, angiogenesis, and cell differentiation and proliferation, thereby playing a therapeutic role in gastric cancer (Liu, et al., 2018). This evidence concerns the gene AKT1 and gastric cancer.