NLRP3 and colitis: Experiments by Zhang et al. (2021b) found that Schisandrin B, the main ingredient of Schisandra chinensis, could not only relieve intestinal inflammation but also suppress the leucine-rich repeat, pyrin domain-containing 3 (NLRP3) inflammasome, and nucleotide-binding oligomerization domain in in vivo and in vitro models of colitis.