MFN2 and Charcot-Marie-Tooth disease type 2A1: For example, pathogenic variants in the mitofusin 2 (MFN2) gene are considered to be associated with Charcot–Marie–Tooth type 2A (CMT2A), with indels contributing to approximately 3.6% of clinical CMT2A cases [28], which is a proportion that is comparable to those identified for exon extension/shrinkage events.