TNF and tuberculosis: To decipher the genetic predisposition for DIH in TB patients taking TB drugs, we performed an association analysis of 14 pharmacogenetic variants in genes NAT2, ABCB1, SLC01B1, NF-κB1, TNF-α, CUX2 and AGBL4, and the results show that the investigated variants are reported to be associated with DIH and ADRs (Table 3).