RT‐qPCR showed significantly higher levels of TGF‐β1, CD206, CD163 and Arginase‐1 mRNA, which indicates an M2‐like immunophenotype, in macrophages selected from IH exosomes or RA miR‐106a‐5p mimics exosomes group than RA exosomes group, which was abolished by inhibition of miR‐106a‐5p in IH exosomes (Figure 11b–e). The gene discussed is TGFB1; the disease is isolated hemihyperplasia.