Indeed, a significant correlation has been established between high HMGA2 expression and reduced overall survival in patients with diverse cancer types [122], including breast [63–67], lung [68–70], colorectal [71–74], prostate [75–77], gastric [78–80], liver [81, 82], thyroid [83–85], bladder [86, 87], pancreatic [123–125] and ovarian [126, 127] cancers. The gene discussed is HMGA2; the disease is cancer.