PPARGC1A and renal cell carcinoma associated with Xp11.2 translocations/TFE3 gene fusions: A more potent effect on cell viability was observed upon treatment with a selective PPARGC1A inhibitor, SR-1829230 and the mitochondrial respiration inhibitor oligomycin in tRCC cell lines with various TFE3 fusions (Fig. 4c–g).