PARP1 and necrotizing enterocolitis: Western blot analysis showed that upon treatment with 3-AB, the increased expression of parthanatos-associated proteins PARP1 and PAR in NEC intestinal tissues was substantially attenuated (p < 0.05, p < 0.01 versus NEC mice) (Fig. 4E–G), demonstrating that administration of 3-AB suppresses the occurrence of parthanatos in the intestinal epithelium during experimental NEC.