Also, it has shown to exert its antitumoral activity via blocking TGFβ‐induced SMAD activation, suppressing TGFβ‐ and HGF‐induced cell invasion and migration in NSCLC cells, and directly inhibiting TGFβRI kinase activity in a competitive inhibitory manner [257]. The gene discussed is TGFB1; the disease is non-small cell lung carcinoma.