In the IRI‐induced renal fibrosis model, the gross renal morphology, results of histochemistry staining, and fibrotic marker expression levels were recapitulated and consistent with that in the UUO model (Figure S2, Supporting Information), thus corroborating the pathogenic role of FOXK1 in renal fibrosis development in mice. The gene discussed is FOXK1; the disease is renal fibrosis.