Previous studies from others have documented the capacity of FOXK1 to bolster FAO in preadipocytes via regulating relevant genes.[27, 31] It raises the question of whether FOXK1 orchestrates two metabolism pathways of FAO and glycolysis in TECs concomitantly in the context of renal fibrosis, which needs to be addressed in the future. This evidence concerns the gene FOXK1 and renal fibrosis.