FOXK1 and renal fibrosis: FOXK1 is a transcription factor involved in glucose metabolism, cell proliferation, and autophagy, and the functions are exercised mainly through transcriptional regulation of its target genes.[26, 27, 31, 32] To explore the transcriptional regulatory mechanisms underlying the roles of FOXK1 in renal fibrosis, we performed chromatin immunoprecipitation‐sequencing (ChIP‐seq) to analyze the genome‐wide distribution of FOXK1 in HK‐2 cells (Figure 4A).