TGFB1 and gastric cancer: In addition, various insults such as the acute insufficiency of oxygen supply, inflammation, and TGF‐β1 activation have been found able to spur the glycolysis in TECs[14, 18, 53, 54, 55] TGF‐β1 is the powerful inducer of FOXK1 expression and activation in different cells, including gastric cancer cells, hepatocyte.[20, 56, 57] These findings lead us to speculate that the initiation of FOXK1 expression is the common pathway leading to the metabolic shift to glycolysis in TECs under distinct conditions.