For example, FAXC (failed axon connections homolog, metaxin like GST domain containing; faxca and faxcb in zebrafish) has been reported in a de novo 6q16.1 deletion region identified in a 3-year-old female case by exome sequencing which may contribute to her developmental delay [51], but its expression and function were almost unknown. Here, FAXC is linked to Global developmental delay.