The 44 genes were analyzed in UALCAN one by one, and the analysis showed that 12 genes were differentially expressed in HCC (MCM4 (Figs. 5a, 6a), POLA1 (Figs. 5b, 6b), MCM6 (Figs. 5c, 6c), MCM3 (Figs. 5d, 6d), RBBP4 (Figs. 5e, 6e), DNA2 (Figs. 5f, 6f), AP2B1 (Figs. 5g, 6g), KIF11 (Figs. 5h, 6h), KIF23 (Figs. 5i, 6i), TUBA1B (Figs. 5j, 6j), KIF14 (Figs. 5k, 6k), NUDT21 (Figs. 5l, 6l)), and their expression was closely related to the overall survival rate of HCC patients. The gene discussed is MCM3; the disease is hepatocellular carcinoma.