The 44 genes were analyzed in UALCAN one by one, and the analysis showed that 12 genes were differentially expressed in HCC (MCM4 (Figs. 5a, 6a), POLA1 (Figs. 5b, 6b), MCM6 (Figs. 5c, 6c), MCM3 (Figs. 5d, 6d), RBBP4 (Figs. 5e, 6e), DNA2 (Figs. 5f, 6f), AP2B1 (Figs. 5g, 6g), KIF11 (Figs. 5h, 6h), KIF23 (Figs. 5i, 6i), TUBA1B (Figs. 5j, 6j), KIF14 (Figs. 5k, 6k), NUDT21 (Figs. 5l, 6l)), and their expression was closely related to the overall survival rate of HCC patients. This evidence concerns the gene MCM6 and hepatocellular carcinoma.