Differential genes mainly focus on cholesterol biosynthesis, tumor cell cycle, negative cell cycle regulation, cell stress response, DNA repair, liver development, G1/ s specific transcription, DNA-binding transcription factor activity regulation, idp53 downstream pathway, PID, ATF2 pathway, fissile cell response to astralization, tp53 transcriptional regulation and other pathways. This evidence concerns the gene ATF2 and neoplasm.