During the acute febrile phase of infection, patients with DHF and DWC exhibitedelevated CXCL-8 (p-value < 0.01) comparedwith those with DF (Figure 2A).Furthermore, patients with DHF and DWC exhibited increased CXCL-10 serum levels(p-value < 0.01) compared to those with DF (Figure 2B). Here, CXCL8 is linked to infection.