ADIPOQ and obesity due to melanocortin 4 receptor deficiency: Many studies describe a link between cancer and diabetes; factors such as hyperglycemia, hyperinsulinemia, insulin resistance, obesity, oxidative stress, inflammation, increased leptin, and decreased adiponectin levels, increased IGF-1 concentrations, and genetics have been investigated as critical components in the relation between cancer and diabetes [14, 16, 17].