NFE2L2 and leukemia: In addition, overexpression of Nrf2 in BM-MSCs promotes leukemia cell infiltration into extramedullary organs, which provides a new target for developing effective drugs for the treatment of B-ALL, lays an experimental foundation to explore the possible mechanisms related to leukemia cell growth and invasion, and provides a reference for inhibiting B-ALL infiltration in extramedullary organs.