BCL2 and Cognitive impairment: It improved cognitive impairment and neuronal injury in rats by reducing the expression of TNF-α, IL-1β, COX-2, decreasing the Bax/Bcl-2 ratio, levels of Aβ1-42 and active-caspase-3, as well as IκB-αdegradation and p-NF-κB p65 activation (Zeng et al., 2019).