IGFBP7 and hyperemesis gravidarum: Common variants of IGFBP7 are susceptibility loci for the diagnosis of pregnancy-related nausea and vomiting (Fejzo et al., 2019b), with serum levels of IGFBP7 significantly increased in hyperemesis gravidarum women at 12 weeks of pregnancy (Fejzo et al., 2019a).