The ROC curves indicated that in the OSA dataset GSE38792, the AUC values for ASS1, HDAC2, SIRT3, and VEGFA are 0.762, 0.812, 0.775, and 0.812, respectively (all above 0.7), suggesting their high accuracy in predicting the correct classification of case and normal groups. Here, HDAC2 is linked to obstructive sleep apnea syndrome.